hyperalgesia相关论文
骨关节炎是一种好发于中老年人群的慢性退行性关节疾病。疼痛是骨关节炎患者最主要的症状，持续疼痛会影响治疗结局。因此，有效的疼痛......
本次年鉴介绍钙离子通道阻断剂镇痛治疗相关文献，包括其作用机制、镇痛效果、合适剂量的选择，特别介绍N型钙通道阻断剂芋螺毒素（Bu8）治......
Pramipexole, a dopamine D3/D2 receptor-preferring agonist, attenuates reserpine-induced fibromyalgia
Fibromyalgia (FM) is a complex pathology described as persistent hyperalgesia including somatic and mood dysfunctions, d......
Nociception is an important physiological process that detects harmful signals and results in pain perception.In this re......
The Mechanism of Hyperalgesia and Anxiety Induced by Remifentanil:Phosphorylation of GluR1 Receptors
研究目的: Theanteriorcingulatecortex(ACC)playsakeyroleinregulatingmoodinanimals,especiallyanxiety,andisalsoabrainregiont......
Transcutaneous electrical acupoint stimulation alleviates remifentanil-induced hyperalgesia in patie
Background: Remifentanil is commonly used in general anesthesia due to its unique pharmacokinetic characteristics-a pred......
Transcutaneous electrical acupoint stimulation alleviates remifentanil-induced hyperalgesia in patie
Background: In this prospective,randomized,double-blind study,we verified the hypothesis that TEAS can alleviate remifen......
Cannabinoid receptor-2 contribute to the regulation of electroacupuncture on expression of β-endorph
Objective It has been reported that EA-produced analgesia is mediated by endogenous opioid systems in uninjured and infl......
The role of Delta opioid receptor in remifentanil induced hyperalgesia by regulating the trafficking
Numerous studies have demonstrated that intraoperative remifentanil infusions have been associated with postoperative op......
Retrograde nerve growth factor signaling modulates tooth mechanical hyperalgesia induced by orthodon
Orthodontic tooth movement elicits alveolar bone remodeling and orofacial pain that is manifested by tooth mechanical hy......
BACKGROUND Thallium poisoning is rare and difficult to recognize.Early diagnosis and treatment of thallium-poisoned pati......
Using tail-flick latency as the nociceptive index and von Frey hair to measure the mechanical allodynia, the aim of the ......
目的探讨预防性皮下注射氯胺酮对瑞芬太尼诱导大鼠痛觉过敏的治疗作用及对脊髓背角钾氯共转运体-2(K＋/Cl－cotransporter 2，KCC2)表达......
目的 比较曲马多和氯胺酮预防雷米芬太尼麻醉颅脑手术患者术后痛觉过敏的效果.方法行颅脑幕上肿瘤切除术患者150例,按随机数字表......
目的探讨不同剂量瑞芬太尼对妇科腹腔镜手术镇痛效果和对痛觉过敏的影响。方法将90例妇科腹腔镜手术患者按随机数字表法分为A组、B......
Possible mechanism underlying analgesic effect of Tuina in rats may involve piezo mechanosensitive c
OBJECTIVE:To demonstrate the analgesic effect of Tuina mainly from mechanically sensitive ion channels in peripheral mye......
Gua Sha attenuates thermal hyperalgesia and decreases proinflammatory cytokine expression in serum i
OBJECTIVE:To investigate the analgesic effect of Gua Sha and its underlying mechanism in rats with noncompressive lumbar......
目的 探索不同频率超声辐照对炎性痛的缓解效果及机制.方法 45只新西兰大白兔,分为3组,1 MHz超声辐照组,0.2 MHz超声辐照组,假照组......
目的 观察异丙酚对急性吗啡耐受小鼠痛阈的影响.方法 健康雌性小鼠56只,随机分成7组(n=8):吗啡异丙酚组1(MP1)、吗啡异丙酚组2(MP2......
【摘要】 瑞芬太尼因其起效迅速和消除不依赖输注时间而广泛用于静脉麻醉,但其所诱发的痛觉过敏现象却越来越受到重视。对瑞芬太尼......
Effect of Electro-acupuncture Stimulation of Ximen (PC4) and Neiguan (PC6) on Remifentanil-induced B
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目的 研究神经损伤即刻给予钠离子通道阻滞剂布比卡因对交感芽生症状产生的抑制作用.方法 将慢性压迫性损伤(CCI)模型大鼠随机分为......
目的:研究完全弗氏佐剂(CFA)外周注射诱导的趋化因子干扰素诱导蛋白10(IP-10)在局部皮肤的表达,以及JNK激酶抑制剂对CFA诱导的疼痛......
目的:观察牙髓炎大鼠三叉神经节初级感觉神经元及牙周组织中疼痛及炎症相关因子的表达变化,探讨三叉神经参与牙髓病理改变及炎性疼......
最新的研究发现,帕瑞昔布可以有效缓解健康受试者短期输注瑞芬太尼后诱导的痛觉过敏.本研究旨在探索临床实践中帕瑞昔布对短期输注......
目的:瑞芬太尼(RF)诱发的阿片源性痛觉过敏抑制了其在临床麻醉的使用.脊髓星形胶质细胞的活化可能与其相关.本实验探讨RF诱发痛觉......
目的 观察ciproxifan在福尔马林痛觉试验中的镇痛作用,并探讨其可能的机制.方法 小鼠足底皮下注射2%福尔马林,观察ciproxifan的镇......
,Intracisternal or intrathecal glycine, taurine, or muscimol inhibit bicuculline-induced allodynia a
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Reversibility of central neuronal changes in patients recovering from gallbladder stones or acute ch
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生......
Effect of Touch-stimulus on the Expression of C-fos and TrkA in Spinal Cord Following Chronic Constr
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生......
目的探讨小剂量舒芬太尼联合帕瑞昔布钠对瑞芬太尼麻醉后术后痛觉过敏的预防效应。方法将120例择期全麻下行腹部手术患者按随机数......
目的 探讨(牙合)干扰去除时间与大鼠咀嚼肌机械痛觉过敏恢复的关系,为临床咬合治疗时机的选择提供实验依据.方法 通过对雄性SD大鼠......
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目的研究束缚应激对大鼠咬肌区域痛觉敏感及三叉神经脊束核尾侧亚核（spinal trigeminal nucleus caudalis，Vc）中神经元、星形胶质细胞......
Autologous nucleus pulposus transplantation to lumbar 5 dorsal root ganglion after epineurium discis
Background Nucleus pulposus of intervertebral discs has proinflammatory characteristics that play a key role in neuropat......
【目的】探讨硬膜外腔注入0．2％罗哌卡因对全麻下阑尾炎手术患者痛觉过敏的影响。【方法】选择2010年5月至2014年2月本院收治的100例......
[目的] 探讨在吗啡引起的痛觉超敏状态下,SD大鼠延髓头端腹内侧区电压门控钙通道(voltage-gated calcium channels, VGCCs)蛋白的......
Effect of dexmedetomidine on mechanical pain threshold and emergence agitation after laparoscopic my
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
【摘要】 目的 探讨帕瑞昔布钠对瑞芬太尼麻醉后痛敏反应的抑制作用,为临床合理应用瑞芬太尼提供理论指导。方法 选择ASAⅠ~Ⅱ级腹......
神经病理性疼痛程度重、治疗效果差,严重影响患者生活质量.神经病理性疼痛的病因有创伤、压迫、神经毒性药物、感染、自身免疫性疾......
目的 探讨新生期伤害性结直肠刺激(colorectal irritation,CI)对幼鼠内脏痛觉敏感性影响,观察幼鼠腰骶段脊髓背角Fos蛋白表达,探讨......
Expression of acetylated histone 3 in the spinal cord and the effect of morphine on inflammatory pai
In this study, a rat model of inflammatory pain was produced by injecting complete Freund's adjuvant into the hind paw, ......
近20年来,疼痛感觉研究的重要发现之一是:外周组织损伤能调节背根神经节和中枢神经某些早期基因(immediate early gene)和参与伤害......
目的 评价一氧化氮(NO)在神经病理性痛大鼠脊髓敏化中的作用.方法 成年雄性Wistar大鼠32只,体重200～300 g,随机分为4组(n=8):假手术......
背景 阿片类药物是治疗中、重度疼痛的主要药物,长时间应用可出现阿片诱发的痛觉过敏和耐受,而增加药物剂量可造成更严重的痛觉过......
目的 确定氯胺酮抑制瑞芬太尼致患者腹腔镜胆囊切除术后痛觉过敏的量效关系.方法 择期全麻下腹腔镜胆囊切除术患者15例,年龄40～60岁......
目的 探究Apelin在尾核内对大鼠的痛觉调制作用及其可能的作用机制.方法 采用辐射热作为伤害性刺激,以安静状态下大鼠的甩尾潜伏期......
目的 研究大鼠切口痛模型中右美托咪定(DEX)对瑞芬太尼诱发的痛觉过敏的影响.方法 60只雄性SD大鼠随机均分成5组:对照组(C),切口痛......
目的 观察神经病理性疼痛大鼠背根神经节(DRG)神经元中小白蛋白(PV)的分布特征及表达变化.方法 成年雄性SD大鼠42只,随机分为空白......
目的 探讨中枢敏化和和外周敏化在瑞芬太尼诱发炎性痛大鼠痛觉过敏中的作用.方法 雄性SD大鼠21只,体重200～300 g,采用随机数字表法,......
